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Updated: May 22, 2026

Enhancing Tumor Content through Tumor Macrodissection
Published on: February 12, 2022
Primary cardiac diffuse large B-cell lymphoma, non-germinal centre B-cell type in an immunocompetent woman
Dawei Liu1, Huijuan Shi, Zunfu Ke
1Department of Pathology, The First Affiliated Hospital and Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Abstract:
Primary cardiac lymphomas are extremely rare and always occur in immunodeficient persons. Here, we report a very rare case of a primary cardiac diffuse large B-cell lymphoma in an immunocompetent 41-year old woman. Echocardiography and computed tomography revealed a mass measuring 74 mm 49 mm in the right atrium. No tumour formations were recognized in other organs. Laboratory data did not reveal immunosuppression, and the human immunodeficiency virus was negative. Histological and immunohistochemical studies showed that the cardiac tumour was diffuse large B-cell lymphoma, non-germinal centre B-cell type. Epstein-Barr Virus-encoded small RNA was negative by in situ hybridization. The patient died 6 months after the operation.
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