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Assessing coronary disease in symptomatic women by the Morise score
Susie N Hong1, Jennifer H Mieres, Jill E Jacobs
1Department of Medicine, Division of Cardiology, New York University School of Medicine, New York, New York 10016, USA. snh73@yahoo.com
Insights
The Morise score is a more accurate tool than the Diamond-Forrester score for assessing coronary artery disease (CAD) risk in women. This simple clinical risk score improves the identification of women who need further cardiac evaluation.
Area of Science:
- Cardiology
- Medical Diagnostics
- Risk Assessment
Background:
- Early detection of coronary artery disease (CAD) in women is crucial due to poorer outcomes compared to men.
- The study investigates the Morise score, a clinical risk assessment tool, for evaluating CAD in symptomatic women.
Purpose of the Study:
- To assess the diagnostic value of the Morise score for CAD using computed tomography coronary angiography (CTCA).
- To compare the performance of the Morise score against the established Diamond-Forrester risk assessment tool in women.
Main Methods:
- 140 women with chest pain syndromes underwent CTCA for CAD assessment.
- Patients were stratified for CAD risk using both Morise and Diamond-Forrester scores.
- Coronary artery stenosis and total coronary calcium were quantified via CTCA and Agatston scores.
Main Results:
- The Morise score showed a significant correlation with coronary calcium scores and the presence/degree of CAD.
- Morise score demonstrated higher accuracy (66% vs. 48%) and sensitivity (56% vs. 16%) compared to Diamond-Forrester.
- Diamond-Forrester stratified a higher percentage of women into low-risk categories (7% vs. 5%) compared to Morise.
Conclusions:
- The Morise score outperformed the Diamond-Forrester score in assessing CAD risk in women.
- A simple history and physical examination, as utilized by the Morise score, are powerful tools for identifying women at risk for CAD.
Background:
Early identification of coronary artery disease (CAD) among symptomatic women is critical given their worse outcomes as compared to men. We evaluated the value of the Morise score, a simple clinical risk score, for the assessment for CAD as determined by computed tomography coronary angiography (CTCA) and compared it to the Diamond-Forrester risk assessment.
Methods:
One hundred forty women (mean age, 64±11 years) with chest pain syndromes and no known CAD referred for CTCA were analyzed. Patients were risk stratified for likelihood of CAD by Morise and Diamond-Forrester scores. The presence and degree of CAD were determined by CTCA and classified as normal, nonobstructive (<50% stenosis), or obstructive (>50% stenosis). Total coronary calcium was calculated based on Agatston scores.
Results:
When risk was assessed by Morise vs. Diamond-Forrester, 5% vs. 7% of women were stratified as low, 41% vs. 82% as intermediate, and 54% vs. 11% as high risk for CAD, respectively. CAD was present in 95 (68%) patients; 22 (16%) had obstructive CAD, and 73 (52%) had nonobstructive CAD. Morise scores significantly correlated with calcium scores (p<0.001) as well as the presence and degree of CAD (p<0.0001). Morise scores also demonstrated significantly higher accuracy (66% vs. 48%, p<0.005) and higher sensitivity (56% vs. 16%, p<0.001) but lower specificity (82% vs. 97%, p<0.05) when compared to Diamond-Forrester risk assessment.
Conclusions:
The Morise score performed better than Diamond-Forrester for CAD risk assessment, which highlights the importance and power of a simple history and physical examination in determining women at risk for CAD.
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