Assessing coronary disease in symptomatic women by the Morise score

Susie N Hong1, Jennifer H Mieres, Jill E Jacobs

  • 1Department of Medicine, Division of Cardiology, New York University School of Medicine, New York, New York 10016, USA. snh73@yahoo.com

Insights

The Morise score is a more accurate tool than the Diamond-Forrester score for assessing coronary artery disease (CAD) risk in women. This simple clinical risk score improves the identification of women who need further cardiac evaluation.

Area of Science:

  • Cardiology
  • Medical Diagnostics
  • Risk Assessment

Background:

  • Early detection of coronary artery disease (CAD) in women is crucial due to poorer outcomes compared to men.
  • The study investigates the Morise score, a clinical risk assessment tool, for evaluating CAD in symptomatic women.

Purpose of the Study:

  • To assess the diagnostic value of the Morise score for CAD using computed tomography coronary angiography (CTCA).
  • To compare the performance of the Morise score against the established Diamond-Forrester risk assessment tool in women.

Main Methods:

  • 140 women with chest pain syndromes underwent CTCA for CAD assessment.
  • Patients were stratified for CAD risk using both Morise and Diamond-Forrester scores.
  • Coronary artery stenosis and total coronary calcium were quantified via CTCA and Agatston scores.

Main Results:

  • The Morise score showed a significant correlation with coronary calcium scores and the presence/degree of CAD.
  • Morise score demonstrated higher accuracy (66% vs. 48%) and sensitivity (56% vs. 16%) compared to Diamond-Forrester.
  • Diamond-Forrester stratified a higher percentage of women into low-risk categories (7% vs. 5%) compared to Morise.

Conclusions:

  • The Morise score outperformed the Diamond-Forrester score in assessing CAD risk in women.
  • A simple history and physical examination, as utilized by the Morise score, are powerful tools for identifying women at risk for CAD.
Abstract

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...