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Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
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Published on: May 6, 2014

Treatment with anti-inflammatory drugs in community-acquired pneumonia

S C A Meijvis1, E M W van de Garde, G T Rijkers

  • 1Department of Internal Medicine, St. Antonius Hospital, Nieuwegein, The Netherlands. s.meijvis@antoniusziekenhuis.nl

Journal of Internal Medicine
|May 16, 2012
PubMed

Insights

Pneumonia

Area of Science:

  • Medical Science
  • Immunology
  • Pharmacology

Background:

  • Pneumonia presents with variable severity, from mild symptoms to fatal septic shock.
  • Excessive inflammation, despite antibiotics, causes damage and contributes to poor outcomes.
  • Rising antibiotic resistance necessitates novel therapeutic strategies.

Purpose of the Study:

  • To review the inflammatory processes in pneumonia.
  • To discuss current and future anti-inflammatory adjuvant therapies for pneumonia.

Main Methods:

  • Literature review of inflammatory responses in pneumonia.
  • Analysis of proposed adjuvant treatments including corticosteroids, statins, macrolides, and Toll-like receptor antagonists.

Main Results:

  • Excessive inflammation is a key factor in pneumonia severity and complications.
  • Several adjuvant therapies show promise in modulating the immune response.

Conclusions:

  • Adjuvant anti-inflammatory therapy is crucial for improving pneumonia prognosis.
  • Corticosteroids, statins, macrolides, and TLR antagonists are potential future treatments.

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