Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies VI: Voiding Cystourethrography and Cystography01:22

Imaging Studies VI: Voiding Cystourethrography and Cystography

Voiding Cystourethrography (VCUG) and Cystography are specialized radiographic procedures used to examine the structure and function of the bladder and urethra.Voiding Cystourethrography (VCUG)A Voiding Cystourethrogram (VCUG) is a diagnostic imaging procedure that assesses the anatomy and function of the lower urinary tract. It focuses on the bladder, bladder neck, and urethra, helping detect abnormalities such as vesicoureteral reflux (VUR)—the backward or reverse flow of urine into the...
Urologic Endoscopic Procedure: Cystoscopic Examination01:28

Urologic Endoscopic Procedure: Cystoscopic Examination

Meaning of Cystoscopic Examination:Cystoscopy is an essential diagnostic tool in urology that is used to assess the structure and function of the genitourinary system. It provides a direct view of the urethra, bladder, and, in some cases, the ureteral openings. This procedure helps detect structural abnormalities, infections, cancers, and blockages in the urinary tract. There are two types of cystoscopy:Flexible cystoscopy is commonly performed in outpatient settings due to its less invasive...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Predicting the need for long-term care: development and comparative evaluation of advanced machine learning models].

Zeitschrift fur Gerontologie und Geriatrie·2026
Same author

A standardized approach to characterize hysteresis in 2D-materials-based transistors for stability benchmarking and performance projection.

Nature communications·2025
Same author

Gender Disparities in Health-related Quality of Life Outcomes Following Radical Cystectomy for Bladder Cancer.

European urology focus·2025
Same author

Extending CARDIO:DE: Additional annotation guidelines and evaluation of NLP approaches for clinical applications.

International journal of medical informatics·2025
Same author

<sup>68</sup>Ga-FAPI and <sup>18</sup>F-FAPI PET/CT for detection of nodal metastases prior radical cystectomy in high-risk urothelial carcinoma patients.

European journal of nuclear medicine and molecular imaging·2025
Same author

[<sup>68 </sup>Ga]Ga-FAPI-46 PET/CT for locoregional lymph node staging in urothelial carcinoma of the bladder prior to cystectomy: initial experiences from a pilot analysis.

European journal of nuclear medicine and molecular imaging·2024
Same journal

On the Memoryless Property in Markov Models for NMIBC Cost-Effectiveness Analysis.

The Journal of urology·2026
Same journal

Multi-institutional Assessment of Performance Metrics for MRI-targeted Transperineal Prostate Biopsy.

The Journal of urology·2026
Same journal

Urinary Supersaturation in a Randomized Trial among Individuals with Recurrent Nephrolithiasis comparing Empiric versus Selective Preventive Therapy: The URINE Trial.

The Journal of urology·2026
Same journal

The FDA Should Allow More BCG Strains into the US Market: How Recent Landmark Trials Expose a Regulatory Paradox.

The Journal of urology·2026
Same journal

Let's Shift the Focus from Death to Life after Fournier's Gangrene.

The Journal of urology·2026
Same journal

Endourology and Nephrolithiasis.

The Journal of urology·2026
See all related articles

Related Experiment Video

Updated: May 22, 2026

Probe-based Confocal Laser Endomicroscopy of the Urinary Tract: The Technique
06:31

Probe-based Confocal Laser Endomicroscopy of the Urinary Tract: The Technique

Published on: January 10, 2013

Long-term decrease in bladder cancer recurrence with hexaminolevulinate enabled fluorescence cystoscopy.

H Barton Grossman1, Arnulf Stenzl, Yves Fradet

  • 1Department of Urology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

The Journal of Urology
|May 16, 2012
PubMed
Summary
This summary is machine-generated.

Hexaminolevulinate fluorescence cystoscopy significantly reduces bladder cancer recurrence. This advanced detection method offers a longer time to recurrence compared to standard methods, aiding bladder preservation.

More Related Videos

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
11:02

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

Related Experiment Videos

Last Updated: May 22, 2026

Probe-based Confocal Laser Endomicroscopy of the Urinary Tract: The Technique
06:31

Probe-based Confocal Laser Endomicroscopy of the Urinary Tract: The Technique

Published on: January 10, 2013

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
11:02

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development

Published on: October 30, 2013

Area of Science:

  • Urology
  • Oncology
  • Medical Imaging

Background:

  • Nonmuscle invasive bladder cancer (NMIBC) diagnosis and management are critical for patient outcomes.
  • Recurrence remains a significant challenge in NMIBC treatment.
  • Accurate detection of all papillary tumors is essential for effective initial resection.

Purpose of the Study:

  • To evaluate the long-term impact of hexaminolevulinate (HAL) fluorescence cystoscopy on the recurrence rate of papillary, nonmuscle invasive bladder cancer.
  • To compare the efficacy of HAL fluorescence cystoscopy versus standard white light cystoscopy in preventing long-term recurrence.

Main Methods:

  • A prospective, randomized study involving 551 participants with Ta or T1 urothelial bladder cancer.
  • Patients were randomized to either white light cystoscopy or HAL fluorescence cystoscopy.
  • Long-term follow-up data was collected through extended study protocols, assessing recurrence rates over several years.

Main Results:

  • Median follow-up was over 50 months for both groups.
  • Patients in the HAL fluorescence cystoscopy group had a significantly longer median time to recurrence (16.4 months) compared to the white light group (9.4 months).
  • While more patients remained tumor-free longer in the fluorescence group (38% vs. 31.8%), the difference in cystectomy rates was not statistically significant (4.8% vs. 7.9%).

Conclusions:

  • Hexaminolevulinate fluorescence cystoscopy significantly improves the long-term time to recurrence for nonmuscle invasive bladder cancer.
  • There is a trend towards improved bladder preservation with the use of HAL fluorescence cystoscopy.
  • HAL fluorescence cystoscopy represents an advancement in the detection and management of bladder cancer, potentially reducing recurrence rates.