Prolonged urticaria and fever in a toddler
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Published on: September 14, 2018
Lori Broderick1, Adriana H Tremoulet, Jane C Burns
1Department od Medicine, University of California-San Diego, USA. lbroderick@ucsd.edu
Insights
A child with recurrent rashes and fever was diagnosed with Kawasaki disease. Pathological findings revealed neutrophil and lymphocyte infiltration, guiding treatment.
Area of Science:
- Pediatrics
- Immunology
- Dermatology
Background:
- Kawasaki disease is an acute febrile illness primarily affecting young children.
- Early diagnosis and treatment are crucial to prevent coronary artery abnormalities.
Observation:
- A 14-month-old girl presented with fever, conjunctival injection, rash, and irritability.
- She had a history of intermittent urticarial-like rash since 3 months of age.
Findings:
- Pathological evaluation revealed a perivascular infiltrate of neutrophils and lymphocytes.
- The diagnostic workup and therapeutic approach for this complex case are discussed.
Implications:
- This case highlights the importance of considering atypical presentations of Kawasaki disease.
- Understanding the pathological basis can aid in timely diagnosis and management.
Abstract:
We describe a 14-month-old girl who initially presented with 8 days of fever, conjunctival injection, rash, and irritability, admitted with a presumptive diagnosis of Kawasaki disease. Further history revealed intermittent urticarial-like rash since 3 months of age and pathological evaluation showed a perivascular infiltrate of neutrophils and lymphocytes. Here, we discuss the key points surrounding her diagnostic workup and our therapeutic approach.
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