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Updated: May 22, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

[Clinical efficacy of cycloferon in complex therapy of infectious mononucleosis in pediatrics]

E B Kasymova, O A Bashkina, Kh M Galimzianov

    Antibiotiki I Khimioterapiia = Antibiotics and Chemoterapy [Sic]
    |May 17, 2012
    PubMed

    Insights

    Cycloferon treatment in children with infectious mononucleosis accelerated symptom resolution and improved liver function. This antiviral therapy demonstrated safety and reduced hospitalization duration without observed side effects.

    Area of Science:

    • Pediatrics
    • Virology
    • Immunology

    Background:

    • Infectious mononucleosis is a common viral illness in children.
    • Standard therapy for infectious mononucleosis focuses on symptom management.
    • Novel therapeutic approaches are needed to improve patient outcomes.

    Purpose of the Study:

    • To evaluate the efficacy and safety of cycloferon in treating infectious mononucleosis in children.
    • To assess the impact of cycloferon on clinical symptoms and laboratory parameters.
    • To determine if cycloferon can reduce hospitalization duration.

    Main Methods:

    • A randomized controlled trial involving 80 children aged 1-15 years with infectious mononucleosis.
    • Participants were divided into two groups: standard therapy plus cycloferon, and standard therapy alone.
    • Cycloferon was administered for 10 days (intramuscularly or orally).

    Main Results:

    • Cycloferon treatment led to a faster reduction and disappearance of clinical symptoms.
    • Improvements were noted in laboratory indices, including liver protein synthesis.
    • The cycloferon group experienced a reduced hospitalization term.
    • No adverse side effects were reported with cycloferon use.

    Conclusions:

    • Cycloferon is an effective and safe therapeutic option for children with infectious mononucleosis.
    • The drug aids in faster symptom recovery and improves specific laboratory markers.
    • Cycloferon offers a potential benefit in reducing the length of hospital stays for pediatric patients.

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