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Related Experiment Video

Updated: May 22, 2026

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

Predictors of decrease in ankle-brachial index among patients with diabetes mellitus.

J Hoe¹, W-P Koh, A Jin

¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Diabetic Medicine : a Journal of the British Diabetic Association

|May 17, 2012

Summary

Nearly one in five patients with diabetes experience significant peripheral arterial disease progression within two years, even with a normal ankle-brachial index. Regular monitoring and managing risk factors like high cholesterol are crucial for early detection and intervention.

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Area of Science:

Vascular Medicine
Diabetology
Cardiovascular Health

Background:

Peripheral arterial disease (PAD) is a common diabetes complication.
Ankle-brachial index (ABI) screening is vital for PAD detection.
Understanding ABI changes over time is crucial for diabetic patients.

Purpose of the Study:

To investigate the rate of change in ankle-brachial index (ABI) over time in Type 2 diabetes patients.
To identify factors associated with significant ABI decrease in this population.

Main Methods:

Assessed ABI changes in 82 Type 2 diabetes patients over a median of 30 months.
Defined significant ABI decrease as > 0.1 from baseline.
Included patients with baseline ABI > 0.9 and ≤ 1.3.

Main Results:

20.7% of patients showed a significant ABI decrease.
5% developed ABI ≤ 0.9, indicating PAD.
Predictors included higher baseline HbA1c, serum creatinine, increased LDL cholesterol, and retinopathy history.

Conclusions:

Significant PAD progression can occur within two years in diabetic patients with normal baseline ABI.
Annual ABI screening is recommended for high-risk individuals.
Better control of hyperlipidemia, glycemic control, renal impairment, and retinopathy is essential.