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Related Concept Videos

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

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Related Experiment Video

Updated: May 22, 2026

Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

Metagenomics - a guide from sampling to data analysis.

Torsten Thomas1, Jack Gilbert, Folker Meyer

  • 1School of Biotechnology and Biomolecular Sciences & Centre for Marine Bio-Innovation, The University of New South Wales, Sydney, NSW 2052, Australia. t.thomas@unsw.edu.au.

Microbial Informatics and Experimentation
|May 17, 2012
PubMed
Summary
This summary is machine-generated.

Metagenomics uses genomic tools to study microbial communities, advancing ecology and diversity. This review offers practical guidance on methods, data analysis, and sharing for future research.

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Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

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Related Experiment Videos

Last Updated: May 22, 2026

Metagenomic Analysis of Silage
08:43

Metagenomic Analysis of Silage

Published on: January 13, 2017

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples
11:23

Purifying the Impure: Sequencing Metagenomes and Metatranscriptomes from Complex Animal-associated Samples

Published on: December 22, 2014

Area of Science:

  • Microbial Ecology
  • Genomics
  • Bioinformatics

Background:

  • Metagenomics has significantly advanced microbial ecology, evolution, and diversity over the last decade.
  • Numerous research labs are actively involved in metagenomic studies.
  • A growing body of methodological knowledge requires consolidation to guide future research.

Purpose of the Study:

  • To review current opinions and practices in metagenomics.
  • To provide practical guidance on various aspects of metagenomic research.
  • To emphasize the importance of standardization and data sharing.

Main Methods:

  • Review of current literature and expert opinions in metagenomics.
  • Synthesis of practical advice on experimental design and execution.
  • Discussion of bioinformatics tools and data analysis strategies.

Main Results:

  • Comprehensive summary of current metagenomic methodologies.
  • Practical guidance on sample processing, sequencing, assembly, binning, and annotation.
  • Recommendations for statistical analysis, data storage, and data sharing.

Conclusions:

  • Standardized procedures are crucial for assessing and comparing metagenomic datasets.
  • Effective data storage and sharing are increasingly important as dataset generation grows.
  • This review serves as a guide for current and future metagenomic research endeavors.