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Surgical Retrieval, Isolation and In vitro Expansion of Human Anterior Cruciate Ligament-derived Cells for Tissue Engineering Applications
Published on: April 30, 2014
The outcomes after anterior cruciate ligament reconstruction in adolescents with open physes
Hiroyuki Koizumi1, Masashi Kimura, Tamiko Kamimura
1Department of Orthopaedic Surgery, School of Medicine, Gunma University, 3-39-15 Showa-machi, Maebashi, Gunma, 371-0034, Japan. hiroyuki831221@yahoo.co.jp
Purpose:
We evaluated the clinical outcome of anterior cruciate ligament reconstruction (ACLR) in adolescents with open physes and compared those results with adults.
Materials And Methods:
Fifteen adolescents with open physes underwent physeal-sparing double-bundle ACLR using hamstring autograft. The median age of the adolescents was 14 years (range 13-16 years). Forty adults underwent anatomic double-bundle ACLR during the same period of this study. The median age of the adults was 26 years (range 17-39 years). Clinical outcomes were evaluated in terms of manual Lachman test, pivot shift test and the results of KT-2000 arthrometer. Additionally, we evaluated clinical outcome in terms of International Knee Documentation Committee (IKDC) score and Lysholm Knee Scoring Scale. We also evaluated rates of re-rupture.
Results:
No clinically significant growth abnormalities were observed in adolescent cases. In the Lachman test, two of the 15 adolescents had a positive, whereas one of the 40 adults had a positive (n.s.). In the pivot shift test, three of the 15 adolescents had a positive, whereas two of the 40 adults had a positive (n.s.). There was no statistically significant difference between adolescents and adults, in the mean side-to-side difference in KT-2000 measurements (1.5 ± 1.5 mm vs. 1.1 ± 1.9 mm: n.s.), the median IKDC score (96.7 vs. 97.3: n.s.) and Lysholm Scale (99 vs. 98: n.s.), rates of re-rupture (13.3 vs. 7.5 %: n.s.).
Conclusion:
Physeal-sparing ACLR with hamstring autograft in adolescents with open physes resulted in good clinical outcomes similar to those of ACLR in adults without growth abnormalities.

