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A screening programme for hypertension in general practice.

F R Taylor1, S E Gould, N A Taylor

  • 1Janssen Pharmaceutical Ltd., Grove, Wantage, Oxon, UK.

Journal of Human Hypertension
|August 1, 1990
PubMed
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This study identified hypertension in 2.9% of patients aged 35-65. Ketanserin and metoprolol showed similar blood pressure reduction, though metoprolol decreased heart rate more.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Clinical Trials

Background:

  • Hypertension diagnosis and treatment rates are suboptimal.
  • Effective management strategies for hypertension are crucial.

Purpose of the Study:

  • To determine hypertension prevalence in a general practice population.
  • To compare the efficacy of ketanserin versus metoprolol in treating hypertension.

Main Methods:

  • A screening program identified patients with hypertension.
  • A randomized, double-blind trial compared ketanserin and metoprolol.
  • Blood pressure and heart rate were monitored over three months.

Main Results:

  • Overall hypertension prevalence was 2.9%, increasing with age.

Related Experiment Videos

  • Both ketanserin and metoprolol effectively reduced blood pressure.
  • Metoprolol significantly reduced heart rate compared to ketanserin.
  • No major side effects or subjective complaints were reported.

    • Conclusions:

    • Hypertension is prevalent in this age group, with higher rates in older individuals.
    • Ketanserin and metoprolol are effective antihypertensive agents.
    • Metoprolol offers an additional benefit of heart rate reduction.