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Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay
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Proteomic analysis of the microenvironment of developing oocytes

John Twigt1, Regine P Steegers-Theunissen, Karel Bezstarosti

  • 1Department of Obstetrics and Gynecology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Proteomics
|May 17, 2012
PubMed

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Oogenesis02:07

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...