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Morphologic analysis in pathologic myopia using high-penetration optical coherence tomography.

Ichiro Maruko1, Tomohiro Iida, Yukinori Sugano

  • 1Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan. imaruko@fmu.ac.jp

Investigative Ophthalmology & Visual Science
|May 17, 2012
PubMed
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High-penetration optical coherence tomography (HP-OCT) visualized the choroid and sclera in pathologic myopia. The subfoveal sclera was found to be thicker than sclera located 3 mm from the fovea.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Pathologic myopia is characterized by axial elongation and structural changes in the posterior segment of the eye.
  • Understanding the morphologic characteristics of the choroid and sclera is crucial for managing this condition.
  • Current imaging techniques may have limitations in visualizing the full thickness of these posterior ocular layers.

Purpose of the Study:

  • To evaluate the choroidal and scleral morphologic characteristics in eyes with pathologic myopia.
  • To assess the utility of high-penetration optical coherence tomography (HP-OCT) and swept-source OCT (SS-OCT) for visualizing these structures.
  • To compare scleral thickness at different locations around the fovea.

Main Methods:

  • Retrospective evaluation of 58 eyes from 35 patients with pathologic myopia (axial length > 26.5 mm).

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  • Measurements of subfoveal choroidal and scleral thickness using a prototype HP-OCT (1060 nm wavelength).
  • Scleral thickness was also measured 3 mm superior, inferior, nasal, and temporal to the fovea; axial length was measured via optical biometry.

    • Main Results:

    • HP-OCT successfully visualized the full-thickness choroid and sclera in all examined eyes.
    • The mean subfoveal choroidal thickness was 52 ± 38 μm, and the mean subfoveal scleral thickness was 335 ± 130 μm.
    • The subfoveal sclera was significantly thicker than the sclera located 3 mm from the fovea (P < 0.05).

    Conclusions:

    • HP-OCT is effective for visualizing the choroid and sclera in pathologic myopia.
    • The subfoveal sclera is thicker compared to peripheral scleral regions in these eyes.
    • HP-OCT serves as a valuable tool for detailed morphologic analysis in pathologic myopia.