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Updated: May 22, 2026

Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Cytogenetics: past, present and future
Thirumulu Ponnuraj Kannan1, Bin Alwi Zilfalil
1Human Genome Centre, Universiti Sains Malaysia Health Campus, Jln Raja Perempuan Zainab II, 16150 Kubang Kerian, Kelantan, Malaysia.
Abstract:
Fifty years have elapsed since the discovery of the number of human chromosomes in 1956. Newer techniques have been developed since then, ranging from the initial conventional banding techniques to the currently used molecular array comparative genomic hybridisation. With a combination of these conventional and molecular techniques, cytogenetics has become an indispensable tool for the diagnosis of various genetic disorders, paving the way for possible treatment and management. This paper traces the history and evolution of cytogenetics leading up to the current state of technology.
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