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Published on: August 13, 2020
Isosporiasis in HIV/AIDS Patients in Edo State, Nigeria
Akinbo Frederick Olusegun1, Christopher Ehis Okaka, Ricardo Luiz Dantas Machado
1Department of Pathology, University of Benin Teaching Hospital, PMB 1111, Benin City, Edo State, Nigeria.
Background:
The role of opportunistic infections in accelerating disease progression in HIV-positive individuals, leading to quick death, is still receiving serious attention. The objective of this study was to determine the prevalence of Isospora belli infections in HIV-positive patients in Edo State, Nigeria between August 2007 and March 2008.
Methods:
A total of 268 samples from HIV-positive patients and 20 samples from HIV-negative patients were processed using the modified Ziehl-Neelsen staining technique to microscopically identify the presence of I. belli oocysts.
Results:
The overall prevalence of the coccidian was 3.1%. Gender and age had no correlation with the prevalence of the parasite (P > 0.05). There was a significant relationship between isosporiasis and CD4+ T cell counts in HIV-positive patients (OR=11.388, 95% CI= 2.797-46.371, P=0.0004).
Conclusions:
Routine investigation of I. belli in HIV-positive subjects is advocated in tertiary health institutions.
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