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Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

4,7-Dichloro-quinoline.

Amol A Kulkarni, Christopher King, Ray J Butcher

    Acta Crystallographica. Section E, Structure Reports Online
    |May 17, 2012
    PubMed
    Summary
    This summary is machine-generated.

    The study analyzed the molecular structure of a compound, C(9)H(5)Cl(2)N. Both molecules were found to be planar with no significant intermolecular interactions.

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    Published on: October 11, 2019

    Area of Science:

    • Crystallography
    • Organic Chemistry
    • Materials Science

    Background:

    • Understanding molecular geometry is crucial for predicting chemical and physical properties.
    • Planarity in organic molecules can influence electronic properties and intermolecular interactions.

    Purpose of the Study:

    • To determine the precise three-dimensional structure of the title compound, C(9)H(5)Cl(2)N.
    • To assess the planarity of the molecules within the asymmetric unit.
    • To investigate potential intermolecular interactions, specifically C-H⋯Cl contacts.

    Main Methods:

    • Single-crystal X-ray diffraction was employed to obtain the structural data.
    • Analysis of atomic coordinates and bond lengths/angles to confirm planarity.
    • Intermolecular contact analysis was performed using standard crystallographic criteria.

    Main Results:

    • The asymmetric unit contains two molecules of C(9)H(5)Cl(2)N.
    • Both molecules exhibit a high degree of planarity, with root-mean-square deviations of non-hydrogen atoms being 0.014 Å and 0.026 Å.
    • No significant C-H⋯Cl intermolecular contacts were identified.

    Conclusions:

    • The title compound, C(9)H(5)Cl(2)N, crystallizes with two molecules in the asymmetric unit.
    • The determined molecular structure confirms the essential planarity of these molecules.
    • The absence of close C-H⋯Cl contacts suggests limited intermolecular interactions of this specific type in the crystal lattice.