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Updated: May 22, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
The role of suboptimal home-measured blood pressure control for cognitive decline
Teodora Yaneva-Sirakova1, Rumiana Tarnovska-Kadreva, Latchezar Traykov
1Cardiology Clinic, University Hospital 'Alexandrovska', Sofia, Bulgaria.
Insights
Suboptimal home blood pressure readings correlate with early cognitive impairment. Neuropsychological tests effectively identify this in hypertension patients during routine practice.
Area of Science:
- Cardiology
- Neurology
- Gerontology
Background:
- Hypertension is a significant risk factor for cognitive decline.
- Early detection of cognitive impairment is crucial for timely intervention.
- Home blood pressure monitoring offers valuable insights into cardiovascular health.
Purpose of the Study:
- To investigate the association between suboptimal home blood pressure measurements and cognitive function.
- To determine if cognitive screening tests can detect early impairment in hypertensive patients with suboptimal blood pressure.
Main Methods:
- A cohort of 325 treated hypertensive patients (mean age 66.12 years) was studied.
- Participants underwent neuropsychological screening using the Mini-Mental State Examination, Montreal Cognitive Assessment, and Hachinski Ischemic Score.
- Home-measured blood pressure was a key data point.
Main Results:
- A nonlinear correlation was found between early cognitive impairment and suboptimal home blood pressure.
- This relationship is dependent on patient age and other risk factors.
Conclusions:
- Neuropsychological tests are effective for identifying early cognitive impairment in hypertensive patients with suboptimal home blood pressure.
- Integrating these tests into routine practice can improve patient care and outcomes.
Aim:
We aim to analyze if there is any correlation between suboptimal home-/self-measured blood pressure values and the results from neuropsychological screening tests for early cognitive impairment.
Methods:
We studied 325 patients with treated hypertension. Mean age was 66.12 (±10.1) years. There were 119 (36.6%) male and 206 (63.4%) female patients, among them 52 (16%) with atrial fibrillation. Neuropsychological tests performed were the Mini-Mental State Examination, Montreal Cognitive Assessment, and Hachinski Ischemic Score; additionally, home-measured blood pressure was used.
Results:
There is a nonlinear age- and risk factor-dependent correlation between early stages of cognitive impairment and suboptimal home-measured blood pressure.
Conclusion:
The use of specific and sensitive neuropsychological tests for early cognitive impairment in patients with suboptimal home-measured blood pressure is effective in the everyday practice.
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