Luffa echinata Roxb. induces human colon cancer cell (HT-29) death by triggering the mitochondrial apoptosis pathway

Li-Hua Shang1, Chun-Mei Li, Zhao-Yang Yang

  • 1Department of Internal Medicine, The Third Affiliated Hospital of Harbin Medical University, Haping Road 150 of Nangang District, Harbin 150081, China.

Summary

The Luffa echinata Roxb. (LER) fruit extract shows anticancer potential by inhibiting colon cancer cell growth. It induces apoptosis through reactive oxygen species generation and cell cycle arrest, suggesting therapeutic possibilities.