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Imaging characteristics of metastatic chordoma
Riwa Kishimoto1, Tokuhiko Omatsu, Azusa Hasegawa
1Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan. riwa@nirs.go.jp
Purpose:
Our aim was to describe the incidence and sites of metastatic chordomas and show their characteristic computed tomography (CT) and magnetic resonance (MR) findings.
Materials And Methods:
One hundred ninety-eight chordoma patients were registered in the institutional database and were followed up with CT and MR examinations for periods ranging from 1 to 158 months. Clinical features and CT and MR findings of metastatic chordomas were analyzed by two radiologists.
Results:
We counted 86 metastatic sites in 49 of 198 patients. The incidence of metastasis was 24.7 %. Sites of metastases were bone, lung, liver, lymph node, muscle, skin, pleura, cerebellum, cardiac muscle, pericardium, and adrenal gland. Duration from the diagnosis to the first detection of metastasis ranged from 0 to 600 months, with an average of 45.0 months. Osteolytic lesions were most common bone metastases, but osteosclerotic metastasis was also encountered. Metastatic chordoma showed very high intensity on diffusion-weighted (DW) images in 29 of 31 patients.
Conclusion:
Metastases of chordoma are not rare and may occur several years after primary lesion presentation. The high intensity of DW images is characteristic and helpful for detecting metastatic chordoma.