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Tissue Membranes

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Related Experiment Video

Updated: May 22, 2026

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Lumican Extraction from Amniotic Membrane and Determination of its Storage Temperature

Published on: October 14, 2022

Amniotic membrane: from structure and functions to clinical applications.

A C Mamede¹, M J Carvalho, A M Abrantes

¹Biophysics Unit, IBILI, Faculty of Medicine, University of Coimbra, Coimbra, Portugal. ana_mamede@hotmail.com

Cell and Tissue Research

|May 18, 2012

Summary

Amniotic membrane (AM) offers regenerative potential for tissue repair and has shown promise in oncology by inhibiting tumor growth. Its unique properties make it a valuable biomaterial for various medical applications.

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Area of Science:

Regenerative Medicine
Biomaterials Science
Oncology

Background:

Amniotic membrane (AM) is a fetal membrane surrounding the amniotic cavity.
AM cells possess pluripotent properties, making them suitable for tissue transplantation.
AM exhibits anti-inflammatory, anti-bacterial, anti-viral, and anti-angiogenic characteristics.

Purpose of the Study:

To investigate the structure and function of amniotic membrane (AM).
To explore the potential applications of AM in regenerative medicine and oncology.
To highlight the therapeutic properties of AM for tissue reconstruction and cancer therapy.

Main Methods:

Review of existing literature on amniotic membrane structure, properties, and applications.
Analysis of AM's biological characteristics, including its effects on inflammation, angiogenesis, and apoptosis.
Examination of AM's utility in surgical procedures and potential role in cancer treatment.

Main Results:

AM possesses regenerative properties, promoting epithelialization and wound healing.
AM demonstrates anti-cancer effects by impeding tumor angiogenesis, nutrient supply, and metastasis.
AM is a non-tumorigenic tissue with no ethical concerns, facilitating its clinical use.

Conclusions:

Amniotic membrane is a versatile biomaterial with significant potential in ocular surface reconstruction, skin grafting, and tissue engineering.
AM's anti-angiogenic and anti-proliferative properties suggest a promising role in oncological applications.
Further research into AM's therapeutic capabilities could expand its clinical impact across diverse medical fields.