Related Experiment Video
Updated: Jan 25, 2026

A Net Mold-based Method of Scaffold-free Three-Dimensional Cardiac Tissue Creation
Published on: August 5, 2018
Limitations of ranking lists based on cardiac surgery mortality rates
Sabrina Siregar1, Rolf H H Groenwold, Evert K Jansen
1Department of Cardio-Thoracic Surgery, University Medical Center Utrecht, Utrecht, the Netherlands. s.siregar@umcutrecht.nl
Insights
Cardiac surgery mortality rankings are imprecise and fluctuate randomly. This study found significant reshuffling of hospital ranks due solely to chance, discouraging their use for performance comparison.
Area of Science:
- Cardiovascular Surgery
- Health Services Research
- Biostatistics
Background:
- Hospital performance rankings are common in cardiac surgery.
- Previous studies indicated imprecision in these rankings.
- The extent of imprecision and fluctuation in cardiac surgery mortality rankings was unknown.
Purpose of the Study:
- To determine the precision of ranking lists for cardiac surgery mortality rates.
- To assess fluctuations in these rankings over time.
- To evaluate the reliability of hospital comparisons based on mortality data.
Main Methods:
- Utilized data from 46,883 adult cardiac surgery patients in 16 Dutch centers (2007-2009).
- Assessed ranks using crude and adjusted mortality rates (logistic EuroSCORE).
- Calculated rank precision using 95% confidence intervals and analyzed rank reshuffling over 3 years.
Main Results:
- Ranking lists showed considerable reshuffling of hospitals over consecutive years.
- Mean 95% confidence intervals for ranks were 10 (crude) and 8 (adjusted) ranks wide.
- Significant overlap in confidence intervals indicated no material difference between hospital rank statistics.
Conclusions:
- Cardiac surgery mortality rankings are statistically imprecise and subject to random fluctuation.
- Rank reshuffling is expected due to chance alone.
- Discourages the use of ranking lists for comparing cardiac surgery mortality rates due to inherent unreliability.
Background:
Ranking lists are a common way of reporting performance in cardiac surgery; however, rankings have shown to be imprecise, yet the extent of this imprecision is unknown. We aimed to determine the precision of, and fluctuations in, ranking lists in the comparison of cardiac surgery mortality rates.
Methods And Results:
Information on all adult cardiac surgery patients in all 16 cardiothoracic centers in The Netherlands from January 1, 2007, until December 31, 2009, was extracted from the database of the Netherlands Association for Cardio-Thoracic Surgery (n=46883). Ranks were assessed using crude and adjusted mortality rates, using a random effects logistic regression model. Risk adjustment was performed using the logistic EuroSCORE. Statistical precision of ranks was assessed with 95% confidence intervals. Additional analyses were performed for patients with isolated coronary artery bypass grafting. The ranking lists, based on mortality rates in 3 consecutive years, showed considerable reshuffling. When all data were pooled, the mean width of the 95% confidence intervals was 10 ranks using crude and 8 ranks using adjusted mortality rates. The large overlap of the confidence intervals across hospitals indicates that rank statistics were not materially different. Results were similar in the isolated coronary artery bypass grafting subgroup.
Conclusions:
Rankings are an imprecise statistical method to report cardiac surgery mortality rates and prone to (random) fluctuation. Hence, reshuffling of ranks can be expected solely due to chance. Therefore, we strongly discourage the use of ranking lists in the comparison of mortality rates.
More Related Videos
Related Concept Videos
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
Ranks
Spearman's Rank Correlation Test
Spearman's test calculates correlation by...
Wilcoxon Rank-Sum Test
Limiting Reactant
Friedman Two-way Analysis of Variance by Ranks

