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Updated: May 22, 2026

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury

Published on: August 16, 2019

An evidence based blunt trauma protocol.

Raoul van Vugt¹, Digna R Kool, Satish F K Lubeek

¹Department of Surgery, Division of trauma surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. raoul.vanvugt@gmail.com

Emergency Medicine Journal : EMJ

|May 18, 2012

Summary

This summary is machine-generated.

A new diagnostic protocol for blunt high-energy trauma patients is feasible and safe, potentially reducing unnecessary computed tomography (CT) scans and improving radiological evaluation efficiency.

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Published on: April 11, 2025

Area of Science:

Emergency Medicine
Radiology
Trauma Surgery

Background:

Computed tomography (CT) is increasingly used for trauma patient evaluation.
A need exists for standardized protocols in high-energy trauma assessment.
Optimizing radiological workups is crucial for efficient patient care.

Purpose of the Study:

To evaluate the clinical feasibility of a novel diagnostic protocol for adult blunt high-energy trauma patients.
To assess the protocol's impact on the utilization of conventional radiography (CR) and CT scans.
To determine the safety and efficiency of the new protocol in a prospective study.

Main Methods:

Developed an evidence-based flowchart for CR, sonography, and CT appropriateness.
Prospectively enrolled 81 consecutive adult blunt high-energy trauma patients.
Monitored protocol adherence, scan types, procedure times, adverse events, and missed injuries.

Main Results:

Achieved 99% adherence to the protocol for CT utilization.
CT scans were performed in 98% of patients, with high rates for cervical spine (96%) and thoracoabdominal (89%).
Identified potential for omitting CT in 30 patients; CR was incorrectly omitted or performed in 38% of cases. No major adverse events or missed injuries were reported.

Conclusions:

The new diagnostic protocol is feasible and safe for evaluating adult blunt high-energy trauma.
Implementation may reduce unnecessary radiological investigations, particularly CT scans.
The protocol shows promise for optimizing trauma patient radiological workups.