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Updated: May 22, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Microimplant-based mandibular advancement therapy for the treatment of snoring and obstructive sleep apnea: a
Joachim Ngiam1, Hee-Moon Kyung
1Department of Orthodontics, School of Dentistry, Kyungpook National University, Daegu, Korea.
Objective:
To investigate the efficacy of orthodontic microimplant-based mandibular advancement therapies for the treatment of snoring and obstructive sleep apnea (OSA) in adult patients.
Materials And Methods:
Ten adult OSA patients (seven men, three women; mean age 60.00 ± 9.25 years) were each treated with two mandibular orthodontic microimplants attached to a customized reverse face mask for mandibular advancement. Pretreatment and posttreatment outcome measures of microimplant mobility, apnea-hypopnea index, snoring, respiratory movement, and Epworth sleepiness scores were evaluated after 6 months.
Results:
Highly significant reductions in the apnea-hypopnea index, snoring, and sleep variables were observed. Sixteen of the 20 (80%) microimplants were stable and showed no mobility, and four (20%) demonstrated grade 1 or 2 mobility and required removal and reinsertion of a new microimplant.
Conclusions:
Favorable reductions in sleep variables highlight the potential of microimplant-based mandibular advancement therapy as an alternative treatment modality for OSA patients who cannot tolerate continuous positive airway pressure and oral appliance therapy.

