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Secondary focal and segmental glomerulosclerosis associated with single-nucleotide polymorphisms in the genes

Sanjeev Sethi1, Fernando C Fervenza, Yuzhou Zhang

  • 1Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA. sethi.sanjeev@mayo.edu

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
|May 19, 2012
PubMed
Summary

Genetic kidney disease, focal and segmental glomerulosclerosis (FSGS), can be linked to complement factor abnormalities. This study identifies new genetic variants in complement factor H and C3 associated with FSGS.

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