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Processing of Bronchoalveolar Lavage Fluid and Matched Blood for Alveolar Macrophage and CD4+ T-cell Immunophenotyping and HIV Reservoir Assessment
Published on: June 23, 2019
Pulmonary complications in the non-HIV immunocompromised patient
S L Jepson1, M Pakkal, A Bajaj
1Department of Radiology, Glenfield Hospital, University Hospitals of Leicester NHS Trust, UK.
Clinical Radiology
|May 19, 2012
Summary
The number of immunocompromised patients without HIV is rising, leading to more pulmonary complications. This review aids in interpreting imaging to distinguish between infectious and non-infective issues in these patients.
Area of Science:
- Medical Imaging
- Pulmonology
- Immunocompromised Patients
Background:
- Increasing incidence of non-HIV immunocompromised patients due to immunosuppressive therapies and stem cell transplantation.
- Pulmonary complications are a significant cause of morbidity and mortality in this population.
- Challenges in microbiological/pathological diagnosis necessitate advanced imaging assessment.
Purpose of the Study:
- To provide a structured approach for interpreting imaging findings in non-HIV immunocompromised patients.
- To differentiate between infective and non-infective pulmonary complications.
- To guide therapeutic strategies based on imaging interpretation.
Main Methods:
- Review of current literature and imaging techniques.
- Structured interpretation framework for pulmonary imaging.
- Differential diagnosis of common complications based on imaging patterns.
Main Results:
- Detailed description of imaging features for various pulmonary complications.
- Guidance on differentiating infectious etiologies (e.g., fungal, bacterial) from non-infective causes (e.g., organizing pneumonia, edema).
- Emphasis on the role of imaging in early detection and management.
Conclusions:
- Imaging plays a crucial role in the diagnosis and management of pulmonary complications in non-HIV immunocompromised patients.
- A systematic approach to imaging interpretation is essential for accurate diagnosis.
- Timely and accurate diagnosis through imaging can improve patient outcomes.
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