Related Experiment Video
Updated: May 22, 2026
Preterm EEG: A Multimodal Neurophysiological Protocol
Published on: February 18, 2012
Elective high-frequency oscillatory ventilation in preterm neonates: a preliminary investigation in a developing
Gowda Parameshwar Prashanth1, Gyanendra Kumar Malik, Sakal Narayan Singh
1Department of Pediatrics, KLE University's JN Medical College, Belgaum, Karnataka, India. dr.prashanth.gp@gmail.com
Background:
Elective high-frequency oscillatory ventilation (HFOV) in preterm infants is known to be as effective as conventional ventilation in the prevention of bronchopulmonary dysplasia without the risk of increased mortality or brain damage.
Objective:
To document the feasibility and safety of early use of HFOV in preterm neonates with respiratory distress syndrome (RDS) in a resource-limited setting. The primary outcome was survival or death, and the secondary outcome included complication rates observed among the two groups, HFOV and synchronised intermittent mandatory ventilation (SIMV).
Method:
Prospective, single-centre, non-crossover, and case-control design comparing outcome of HFOV with synchronised intermittent mandatory ventilation (SIMV) in preterm neonates with RDS.
Results:
Preterm infants with RDS and a gestational age of 26-36 weeks were ventilated using either SIMV or HFOV soon after intubation. Twenty-two neonates in the HFOV group and 27 in the SIMV group were considered in the final analysis. Mortality was similar in both the groups for each gestational-age subgroup. There were no statistically significant differences in complication rates between the groups.
Conclusion:
Elective ventilation with HFOV to provide pulmonary support for preterm neonates is feasible in a resource-limited country such as India.
Related Concept Videos
01:29Mechanical Ventilation I: Indication and Settings
01:23Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
01:20Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
01:29Assessment of Ventilation II: Respiratory Depth and Rhythm
Respiratory depth measures the volume of air inhaled or exhaled during a breath. It can vary from shallow to deep and typically remains consistent when a person is at rest or asleep. Occasionally, individuals will automatically inhale deeply, known as sighing, which inflates the lungs with more air than normal breathing.
To assess respiratory depth, observe the degree of chest excursion or movement:
01:14Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
01:10Atelectasis II: Pathophysiology