Alcohol septal ablation through a bare metal stent after rotative atherectomy: a complex procedure
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Updated: May 22, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Nicolas Combaret1, Géraud Souteyrand, Pascal Motreff
1Department of Cardiology, Gabriel Montpied Hospital, Clermont-Ferrand University Hospital, Clermont-Ferrand, France. n_combaret@chu-clermontferrand.fr
Insights
This case study details a novel two-stage treatment for severe hypertrophic obstructive cardiomyopathy (HOCM) and coronary artery disease. The procedure successfully addressed both conditions sequentially, marking a first in interventional cardiology.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Medical Case Reports
Background:
- Severe hypertrophic obstructive cardiomyopathy (HOCM) presents complex therapeutic challenges.
- Calcified stenosis in the left anterior descending (LAD) coronary artery necessitates careful management to prevent ischemia.
Observation:
- A patient presented with coexisting severe HOCM and significant calcified LAD stenosis.
- The treatment strategy involved a staged approach, prioritizing ischemic heart disease.
Findings:
- Successful angioplasty with stenting of the LAD was performed, followed by alcohol septal ablation for HOCM.
- Catheterization of the septal branch was achieved through the mesh of a previously implanted bare metal stent in the LAD.
Implications:
- This case demonstrates a potentially effective combined interventional strategy for patients with both HOCM and coronary artery disease.
- The findings suggest that trans-stent septal ablation is a feasible technique, offering a new therapeutic option.
Abstract:
We report the case of a patient with severe malignant hypertrophic obstructive cardiomyopathy (HOCM) and calcified stenosis of the proximal and middle left anterior descending (LAD) coronary artery. We elected to treat his ischemic heart disease first. We performed angioplasty of the proximal and middle LAD, after rotative atherectomy, and implanted two bare metal stents. Thirty days later we treated his HOCM by alcohol septal ablation with catheterization of the first septal branch through the mesh of the bare metal stent implanted in the LAD. To our knowledge, this is the first documented report of such a procedure.
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