Related Experiment Video For Breast cancer
Updated: May 22, 2026

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
Published on: April 7, 2017
[Chondrosarcomatous metaplastic carcinoma of the breast, a rare tumor]
P Guillén-Paredes1, L Carrasco-González1, A Chaves-Benito2
1Servicio de Cirugía General y Digestiva, Hospital JM Morales Meseguer, Murcia, España.
Abstract:
Metaplastic carcinomas of the breast are uncommon, accounting for less than 0.2% of all breast cancers. Clinically and radiologically, metaplastic carcinomas are indistinguishable from typical ductal carcinomas, and the diagnosis is made histologically by the finding of a mesenchymal component. We present a case of chondrosarcomatous metaplastic breast carcinoma whose definitive diagnosis required immunohistochemical techniques to confirm the malignant epithelial component of the tumor. Accurate diagnosis is important because this tumor behaves differently: it usually spreads through the blood (whereas typical epithelial carcinomas spread through the lymph vessels), metastases present during follow-up rather than before diagnosis, and the five-year survival rate is 35%.
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