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[Bronchodilation induced by fenoterol in asthmatic patients: comparison of jet nebulization and spacer device]
N Morrone1, J A Freire, C A Pereira
1Clínica Pneumológica, Hospital do Servidor, São Paulo.
Objective:
To compare bronchodilation attained by fenoterol administered through a jet nebulizer and through a spacer device.
Type Of Study:
Open, randomized.
Patients:
44 adults with asthma, peak-flow rate varying between 120 and 200 l/min. Patients were divided into two groups. TREATMENT [corrected]: Group A was treated with fenoterol (2.5 mg) with saline to complete 3 ml given through a jet nebulizer; 30 minutes later, an additional dose (1 mg) was given through a 500 ml spacer. Group B was treated with the same dosage, but the spacer [corrected] was used first.
Evaluation:
Peak-flow meter in zero, 30 and 60 minutes.
Results:
No significant difference in bronchodilation was seen between groups A and B.
Conclusion:
Fenoterol through a spacer can replace inhalation in adult asthma patients with non-severe obstruction. Lower cost and home treatment are the main advantages.