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Colonic and breast carcinomas--association or metastases? Report of a case
J J Tjandra1, J A Smith, J P Collins
1Department of Pathology, University of Melbourne, Parkville, Victoria, Australia.
Singapore Medical Journal
|October 1, 1990
Abstract:
There is an increased incidence of colonic carcinoma in patients with breast carcinoma but colonic involvement secondary to breast carcinoma can also occur. The differentiation of the organ or origin (breast vs colon) of the abdominal tumour can be difficult and may benefit from the use of immunohistochemical staining with monoclonal antibodies that react preferentially with colon cancer (JGT) and breast cancer (3E1.2, BC2,BC3). Measurement of Mammary Serum Antigen (MSA) level as detected by the anti-breast monoclonal antibody (3E1.2) was also useful in the classification of tumours of uncertain origin.