[Laboratory diagnosis of renal changes caused by occupational chemical factors]

The problem of early detection of the consequences of toxic action of chemical substances on the kidneys at the working place is becoming one of more important problems in the prophylaxis of renal diseases. The introduction of new sensitive diagnostic methods such as enzyme activity determination or low-molecular-weight proteins measurement in urine has made possible detection of renal damage in the reversible stage. As yet the observations demonstrate that workers exposed in their occupation to heavy metals (cadmium, lead, metalic mercury) and organic solvents should be subjected to special control for detection of renal changes.