Related Experiment Video
Updated: May 22, 2026
Primary Orthotopic Glioma Xenografts Recapitulate Infiltrative Growth and Isocitrate Dehydrogenase I Mutation
Published on: January 14, 2014
Pleomorphic xanthoastrocytoma with malignant transformation and multiple recurrences in an Iranian girl
Fariba Binesh1, Ali Akhavan, Hossein Navabii
1Department of Pathology, Shahid Sadoghi Hospital, Yazd, Iran, Islamic Republic of Iran. binesh44@yahoo.com
Abstract:
Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic tumour of the brain. Some PXAs are accompanied by anaplastic features and are difficult to manage because of frequent recurrences that lead to early death. Well-documented cases of malignant transformation in PXA and of anaplastic PXA are rare in the literature. The authors report a case of PXA with malignant transformation in the right temporo occipital lobe in a 13-year-old Iranian girl.
