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Paediatric acute basilar thrombosis successfully treated with intravenous alteplase

Paulo Rego Sousa1, Rui Vasconcellos

  • 1Paediatric Neurology Unit, Paediatrics Department, Hospital Central do Funchal, Funchal, Portugal. pauloregodesousa@portugalmail.pt

BMJ Case Reports
|May 19, 2012
PubMed

Insights

Acute ischemic stroke is a major cause of childhood death. This study reports a successful case of intravenous recombinant tissue plasminogen activator treatment in a 13-year-old girl with basilar artery thrombosis.

Area of Science:

  • Neurology
  • Pediatric Stroke
  • Thrombotic Disorders

Background:

  • Childhood arterial ischemic stroke presents significant morbidity and mortality.
  • Limited data exists on the safety and efficacy of acute thrombolytic therapies in pediatric arterial ischemic stroke.

Observation:

  • A 13-year-old female presented with acute basilar artery thrombosis.
  • The patient underwent prompt investigation and management.

Findings:

  • Successful treatment with intravenous recombinant tissue plasminogen activator was achieved.
  • This case highlights the potential of thrombolytic therapy in pediatric stroke.

Implications:

  • This case contributes to understanding the management of pediatric arterial ischemic stroke.
  • Further research into thrombolytic therapies for childhood stroke is warranted.

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