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Updated: May 22, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
A father with postpartum psychosis
1Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois, USA. lokesh83@hotmail.com
Insights
Postpartum psychosis, a severe mood disorder, can affect fathers. This case study highlights a male patient experiencing acute mania with psychotic symptoms after his child's birth, successfully treated with medication.
Area of Science:
- Psychiatry
- Perinatal Mental Health
- Psychotic Disorders
Background:
- Postpartum psychosis is a severe mood disorder occurring in the perinatal period.
- It is most commonly linked to postpartum bipolar disorder.
- While typically associated with mothers, paternal postpartum psychosis is a recognized, albeit rare, condition.
Observation:
- A case report details a male patient admitted to a psychiatric unit five days after his wife gave birth.
- The patient exhibited significant concern for his child's well-being, fearing harm.
- He presented with an acute manic episode featuring psychotic symptoms.
Findings:
- The patient received a diagnosis of acute manic episode with psychotic symptoms.
- Treatment involved olanzapine and lithium.
- The patient remained symptom-free on a therapeutic lithium dose three months post-episode.
Implications:
- This case underscores the importance of considering paternal mental health in the postpartum period.
- Psychological stress may precipitate severe mood and psychotic disorders in fathers.
- Early diagnosis and pharmacotherapy, including mood stabilizers like lithium, are crucial for managing paternal postpartum psychosis.
Abstract:
Postpartum psychosis is a rare, however severe mood disorder in the perinatal period. It is most commonly associated with postpartum bipolar disorder. The author reports a case where a male patient with psychosis was admitted to the psychiatric unit 5 days after his wife gave birth to their male child. The patient was very concerned about the well being of his child and was afraid that something bad would happen to his child. The patient was diagnosed with an acute manic episode with psychotic symptoms and treated with olanzapine and lithium. The patient has been continued on therapeutic dose of lithium without any relapse of the symptoms, 3 months after the initial episode. The role of psychological stress in precipitating such a severe mood or psychotic disorder needs to be highlighted.
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