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Related Experiment Video

Updated: May 22, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

Rosuvastatin-induced pemphigoid.

Aizuri A Murad¹, Maureen Connolly, Anne-Marie Tobin

¹Dermatology Department, Adelaide and Meath Hospital, Dublin, Ireland. aiz100@hotmail.com

BMJ Case Reports

|May 19, 2012

Summary

This summary is machine-generated.

Rosuvastatin, a common statin drug, may rarely induce pemphigoid, an autoimmune blistering disease. This case report highlights a potential adverse effect of this widely used medication.

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Area of Science:

Pharmacology
Immunodermatology

Background:

Statins, including rosuvastatin, are frequently prescribed for dyslipidemia.
Immunobullous diseases can be idiopathic or drug-induced, sharing clinical and immunohistological similarities.

Observation:

A case of pemphigoid was observed in a patient taking rosuvastatin.
Rosuvastatin acts as a competitive inhibitor of HMG-CoA reductase.

Findings:

This report details a case of rosuvastatin-induced pemphigoid.
Literature on rosuvastatin-associated pemphigoid is limited.

Implications:

Clinicians should consider rosuvastatin as a potential cause of pemphigoid.
Further investigation into drug-induced immunobullous diseases is warranted.