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Lipid disorders in hospital attendants in Kumasi, Ghana
1Department of Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Insights
Lipid disorders are prevalent in adult patients in Kumasi, Ghana. Early screening and management are crucial for preventing cardiovascular diseases linked to high cholesterol and abnormal lipid levels.
Area of Science:
- Cardiology
- Public Health
- Clinical Biochemistry
Background:
- Lipid disorders represent a significant global health concern, contributing substantially to atherosclerotic cardiovascular diseases.
- Understanding the local prevalence of these conditions is vital for targeted public health interventions.
Purpose of the Study:
- To ascertain the prevalence of lipid disorders among adult patients presenting at Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana.
- To assess lipid profiles, including total cholesterol, HDL, LDL, and triglycerides, in this population.
Main Methods:
- A cross-sectional study was conducted at KATH outpatient clinics.
- 424 adult patients (≥20 years) were recruited, categorized by diabetes mellitus (DM) and systemic hypertension (HPT) status.
- Data collection involved questionnaires, anthropometric measurements, and biochemical analyses for lipid parameters and atherogenic index.
Main Results:
- High prevalence rates were observed: 60% for high total cholesterol (TC), 32% for high triglycerides (TG), 17% for low high-density lipoprotein cholesterol (HDL), and 61% for high low-density lipoprotein cholesterol (LDL).
- Mean lipid values were TC: 5.33 mmol/L, TG: 1.52 mmol/L, HDL: 1.65 mmol/L, and LDL: 3.42 mmol/L.
- The mean atherogenic index (TC/HDL) was 3.40, with 9% exhibiting an index ≥ 5.
Conclusions:
- Lipid disorders are highly prevalent in the adult patient population in Kumasi.
- There is an urgent need to enhance awareness, screening, detection, treatment, and control strategies for lipid disorders in this region.
Background:
Lipid disorders are common worldwide and contribute to a significant proportion of the burden of atherosclerotic cardiovascular diseases.
Objectives:
To determine the prevalence of lipid disorders among patients reporting at Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana.
Design:
Cross-sectional study.
Setting:
Directorate of Medicine and Polyclinic outpatient clinics of KATH.
Participants:
A total of 424 patients, 20 years and over reporting for the first time to KATH were recruited. 77 had neither diabetes mellitus (DM) nor systemic hypertension (HPT) (controls), 94 had only DM, 109 had only HPT and 144 had both.
Methods:
A questionnaire was administered after informed consent. Anthropometric measurements were then taken and blood investigations including total cholesterol (TC), high-density lipoprotein cholesterol (HDL) and triglycerides (TG) were done. Low-density lipoprotein cholesterol (LDL) was calculated using the Friedwald formula. The atherogenic index or ratio was the ratio of TC to HDL.
Results:
The prevalence of lipid abnormalities was 60% for high TC, 32% for high TG, 17% for low HDL and 61% for high LDL. The mean (± standard deviation) TC was 5.33 (± 1.31) mmol/L, mean TG was 1.52 (± 0.81) mmol/L, mean HDL was 1.65 (± 0.57) mmol/L and mean LDL was 3.42 (± 1.22) mmol/L. The mean atherogenic index was 3.40 and 9% of the participants had an atherogenic index more than or equal to 5.
Conclusion:
The prevalence of lipid disorders was high in adult patients in Kumasi and there is the need to increase awareness, screening, detection, treatment and control of these disorders.
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