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Facile Preparation of 4-Substituted Quinazoline Derivatives
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Published on: February 15, 2016

4-(4-Amino-2-fluoro-phen-oxy)-7-meth-oxy-quinazolin-6-ol methanol monosolvate

Wei Huang, Aimin Tan

    Acta Crystallographica. Section E, Structure Reports Online
    |May 19, 2012
    PubMed

    Abstract:

    In the title compound, C(15)H(12)FN(3)O(3)·CH(3)OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, mol-ecules are linked by N-H⋯O and O-H⋯N hydrogen bonds, generating [10-1] chains of alternating main mol-ecules and solvent mol-ecules. Weak C-H⋯O inter-actions are also observed.

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