4-{2-[(E)-Cyclo-pentyl-idene]hydrazin-1-yl}benzene-sulfonamide

Area of Science:

• Crystallography
• Molecular Chemistry

Background:

• Understanding the three-dimensional structure of organic molecules is crucial for predicting their properties and interactions.
• Sulfonamide-containing compounds have diverse biological and material applications.

Purpose of the Study:

• To elucidate the crystal structure and supra-molecular assembly of the title molecule, C(11)H(15)N(3)O(2)S.

Main Methods:

• Single-crystal X-ray diffraction analysis was employed to determine the molecular and crystal structure.
• Analysis of intermolecular interactions, including hydrogen bonds and van der Waals forces, was performed.

Main Results:

• The molecule exhibits a twisted five-membered ring conformation.
• The benzene ring is inclined relative to the imine residue with a specific torsion angle.
• Supra-molecular layers are formed in the bc plane via intermolecular hydrogen bonds between amine, sulfonamide, and imine groups.
• A weak hydrazine hydrogen atom interaction with a sulfonamide oxygen atom was observed.

Conclusions:

• The detailed crystal structure provides insights into the conformational preferences of the molecule.
• The identified supra-molecular architecture highlights the role of hydrogen bonding in organizing molecules in the solid state.
• This structural information can guide the design of related compounds with tailored properties.