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Granulocytic Sarcoma of the Stomach Presenting as Dysphagia during Pregnancy

Anuradha Sekaran1, Santosh Darisetty, Sandeep Lakhtakia

  • 1Department of Pathology Asian Institute of Gastroenterology, 6-3-661 Somajiguda, Hyderabad 500 082, India.

Case Reports in Gastrointestinal Medicine
|May 19, 2012
PubMed

Granulocytic sarcoma also known as extramedullary myeloid sarcoma or chloroma is an uncommon manifestation of leukemia and presents as a deposit of leukemic cells outside the bone marrow. We report a case of a twenty-five-year-old pregnant woman who presented with progressive dysphagia and recurrent postprandial vomiting. Upper GI endoscopy had shown large flat laterally spread nodular lesions in the cardia and proximal body of stomach. Biopsies from the gastric lesion showed granulocytic sarcoma of the stomach. Concurrent peripheral and bone marrow picture was suggestive of acute myeloid leukemia (AML-M4). There is limited reported literature on granulocytic sarcoma of the stomach. Concurrent gastric granulocytic sarcoma involving cardia and AML in pregnancy has not been reported till date.

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