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Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
Renal Corpuscle01:20

Renal Corpuscle

The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
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The Retinoblastoma Gene01:20

The Retinoblastoma Gene

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Renal Tubule and Collecting Duct

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External Anatomy of the Kidney

The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
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Related Experiment Video

Updated: May 22, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
06:38

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Primary renal synovial sarcoma.

Mehmet Gulum1, Ercan Yeni, Murat Savas

  • 1Department of Urology, School of Medicine, Harran University, 63100 Sanliurfa, Turkey.

Case Reports in Urology
|May 19, 2012
PubMed
Summary

Primary renal synovial sarcoma is a rare cancer in young adults. Successful treatment involved radical nephrectomy, highlighting the importance of considering this malignancy in cystic renal masses.

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Area of Science:

  • Oncology
  • Pathology
  • Surgical Oncology

Background:

  • Synovial sarcoma typically presents as a deep-seated tumor near large joints in adolescents and young adults.
  • Primary renal synovial sarcoma is an exceptionally rare entity with uncertain histogenesis.
  • Fewer than 40 cases have been documented in English medical literature.

Observation:

  • This report details two successful cases of primary renal synovial sarcoma treated with radical nephrectomy.
  • The patients presented with cystic renal masses, a presentation that can obscure malignancy.
  • Early suspicion is crucial, particularly in young adults with renal masses.

Findings:

  • Radical nephrectomy proved effective for treating primary renal synovial sarcoma in these cases.
  • The study underscores the rarity and diagnostic challenge of renal synovial sarcoma.
  • Combined surgical resection and ifosfamide-based chemotherapy are standard management strategies.

Implications:

  • Physicians should maintain a high index of suspicion for malignancy, including synovial sarcoma, in cystic renal masses, especially in young adults.
  • Awareness of this rare renal tumor can lead to earlier diagnosis and improved patient outcomes.
  • Further research into the histogenesis and optimal treatment of renal synovial sarcoma is warranted.