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Updated: May 22, 2026

An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
Primary malignant melanoma of the urinary bladder
Jalal Eddine El Ammari1, Youness Ahallal, Mohammed Jamal El Fassi
1Department of Urology, University Hospital Center Hassan II-Fes, Morocco.
Primary melanoma of the urinary bladder is extremely rare, with only 19 cases reported globally. This report details a case of a 71-year-old male with bladder melanoma, highlighting the challenges in diagnosis and treatment.
Area of Science:
- Oncology
- Urology
Background:
- Primary melanoma of the urinary bladder is an exceptionally rare malignancy.
- Fewer than 20 cases have been documented worldwide, often as isolated case reports.
Observation:
- A 71-year-old male presented with a two-month history of hematuria.
- Ultrasonography identified a 5-cm mass in the bladder trigone.
- Transurethral resection of the bladder tumor (TURBT) confirmed malignant melanoma.
Findings:
- Metastatic disease evaluation was negative at the time of diagnosis.
- The patient unfortunately passed away five months post-diagnosis, prior to radical treatment.
Implications:
- This case contributes to the limited literature on primary bladder melanoma.
- It underscores the aggressive nature and poor prognosis often associated with this rare cancer.
- Further research into optimal therapeutic strategies and prognostic factors is warranted.
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