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Updated: May 22, 2026
Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
Published on: September 25, 2019
Segmentation of Multiple Sclerosis Lesions in Brain MR Images Using Spatially Constrained Possibilistic Fuzzy C-Means
Hassan Khotanlou1, Mahlagha Afrasiabi
1Dept. of Computer Engineering, Bu-Ali Sina Univ., Hamedan, Iran, email: {khotanlou, m.afrasiabi}@basu.ac.ir.
Abstract:
This paper introduces a novel methodology for the segmentation of brain MS lesions in MRI volumes using a new clustering algorithm named SCPFCM. SCPFCM uses membership, typicality and spatial information to cluster each voxel. The proposed method relies on an initial segmentation of MS lesions in T1-w and T2-w images by applying SCPFCM algorithm, and the T1 image is then used as a mask and is compared with T2 image. The proposed method was applied to 10 clinical MRI datasets. The results obtained on different types of lesions have been evaluated by comparison with manual segmentations.
