Related Experiment Videos
Autonomic innervation of the equine urinary bladder
D Prieto1, S Benedito, L Rivera
1Departamento de Fisiología, Facultad de Veterinaria, Universidad Complutense de Madrid, Spain.
Anatomia, Histologia, Embryologia
|September 1, 1990
Summary
The equine urinary bladder has abundant autonomic nerves, including catecholaminergic and acetylcholinesterase-positive fibers. These nerves originate partly from ganglion cells within the bladder wall, indicating intrinsic innervation.
Area of Science:
- Veterinary Anatomy
- Neuroscience
- Urology
Background:
- The autonomic nervous system regulates bladder function.
- Understanding equine bladder innervation is crucial for diagnosing and treating urinary disorders.
Purpose of the Study:
- To investigate the distribution and density of intrinsic autonomic nerves in the equine urinary bladder.
- To characterize the types of nerve fibers present using specific markers.
Main Methods:
- Peroxidase-antiperoxidase immunohistochemistry to localize tyrosine-hydroxylase (TH)-positive nerve fibers.
- Histochemical techniques to detect acetylcholinesterase (AChE) activity.
Main Results:
- The equine urinary bladder exhibits a rich autonomic innervation.
- Both catecholaminergic (TH-positive) and AChE-positive nerve fibers are present.
- A portion of these nerve fibers originate intrinsically from ganglion cells within the bladder wall.
Conclusions:
- The equine urinary bladder possesses a complex intrinsic autonomic nerve supply.
- This intrinsic innervation likely plays a significant role in bladder function.
- Findings are consistent with intrinsic autonomic innervation observed in other mammalian bladders.