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Updated: May 22, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Detection of small fenestral otosclerotic lesions by high-resolution computed tomography using multiplanar
Nozomu Mori1, Yoshihiro Toyama, Naruhide Kimura
1Department of Otolaryngology, Faculty of Medicine, Kagawa University, Kagawa, Japan. nozomu@med.kagawa-u.ac.jp
Objective:
The aim of this study was to assess the value of multislice computed tomography (MSCT) using multiplanar reconstruction (MPR) to detect the small fenestral lesions in patients with otosclerosis.
Methods:
MSCT with MPR imaging was used to evaluate 27 ears of 17 patients with otosclerosis (3 male and 14 females) ranging in age from 33 to 69 years with a mean of 49.8 year. MSCT imaging was performed using Aquilion®. Axial spiral scans with a 0.5-mm slice thickness were obtained. The acquired high-resolution data were transferred to a workstation (ALATO VIEW). MPR images were created in the planes parallel to the stapedial crus and then analyzed on the monitor screen by two radiologists (Y.T. and N.K.).
Results:
MPR images showed abnormal findings in 26 of 27 ears with otosclerosis (96%), whereas axial images showed abnormal findings in only 15 of 27 ears (56%). The similar classification between both images was shown only in 9 of 27 ears (33%). In 16 ears (67%) axial images under-evaluated the lesions compared with MPR images. MPR images detected smaller foci than axial images. Air-bone gap at 0.5-4kHz tended to increase dependently on the extension of fenestral lesions evaluated by MPR images.
Conclusion:
MPR images detected fenestral lesions in otosclerosis more frequently and more precisely than axial images. The extent of fenestral lesions observed on MPR images tends to be related to the degree of conductive hearing loss.
Insights
Multiplanar reconstruction (MPR) with multislice computed tomography (MSCT) significantly improves the detection of small fenestral lesions in otosclerosis. MPR imaging offers more precise and frequent identification of these lesions compared to axial images.
Area of Science:
- Otolaryngology
- Radiology
- Medical Imaging
Background:
- Otosclerosis is a common cause of conductive hearing loss.
- Early and accurate detection of fenestral lesions is crucial for effective management.
- Traditional imaging methods may not adequately visualize small lesions.
Purpose of the Study:
- To evaluate the diagnostic value of multislice computed tomography (MSCT) with multiplanar reconstruction (MPR) for detecting small fenestral lesions in otosclerosis patients.
- To compare the efficacy of MPR imaging against standard axial imaging in identifying otosclerotic changes.
Main Methods:
- MSCT imaging with a 0.5-mm slice thickness was performed on 27 ears from 17 otosclerosis patients.
- Multiplanar reconstruction (MPR) images were generated from the high-resolution axial data.
- Two radiologists analyzed both axial and MPR images for fenestral lesions.
Main Results:
- MPR imaging identified abnormal findings in 96% of ears, compared to 56% with axial images.
- Axial images under-evaluated lesions in 67% of cases, missing smaller foci detected by MPR.
- A correlation was observed between the extent of fenestral lesions on MPR and the air-bone gap.
Conclusions:
- MPR imaging is superior to axial imaging for detecting and precisely characterizing fenestral lesions in otosclerosis.
- The findings suggest MPR can aid in assessing the severity of otosclerosis and its impact on hearing loss.

