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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

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Related Experiment Video

Updated: May 22, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
10:31

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Predicting need for allogeneic transfusion after total knee arthroplasty.

Manish S Noticewala1, Jonathan D Nyce, Wenbao Wang

  • 1Center for Hip and Knee Replacement (CHKR), NewYork-Presbyterian Hospital at Columbia University, New York, New York 10032, USA.

The Journal of Arthroplasty
|May 22, 2012
PubMed
Summary

Predicting allogeneic blood transfusions (AllTx) after total knee arthroplasty (TKA) is crucial. Key factors like age, anemia, hemoglobin, and surgical time help identify patients needing AllTx, optimizing blood resource allocation.

Related Experiment Videos

Last Updated: May 22, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
10:31

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Area of Science:

  • Orthopedic Surgery
  • Transfusion Medicine
  • Health Services Research

Background:

  • Total knee arthroplasty (TKA) is frequently associated with significant blood loss.
  • Allogeneic blood transfusions (AllTx) are common but incur costs and strain limited blood resources.
  • Predictive models for AllTx can improve patient management and resource allocation.

Purpose of the Study:

  • To identify preoperative and intraoperative factors predicting the need for AllTx after primary TKA.
  • To develop and validate a predictive model for AllTx requirement in TKA patients.

Main Methods:

  • Retrospective analysis of 644 primary unilateral TKA cases without autologous blood predonation.
  • Evaluation of 31 independent variables for association with AllTx.
  • Development and testing of a predictive model on an independent cohort.

Main Results:

  • 11.0% of TKAs (71 cases) required AllTx.
  • Significant predictors for AllTx included patient age, comorbid anemia, preoperative hemoglobin, and surgical duration.
  • The developed model demonstrated 90% sensitivity and 52.5% specificity in an independent cohort.

Conclusions:

  • Preoperative and intraoperative factors can effectively predict the need for AllTx after TKA.
  • A validated predictive model can aid in managing blood resources and patient care.
  • Further refinement of predictive models may enhance accuracy and clinical utility.