Related Experiment Video
Updated: May 22, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
Rescue human chorionic gonadotropin for false empty follicle syndrome: optimism for successful pregnancy outcome
Joseph O'Brien Doyle1, Jill Amanda Attaman, Aaron Kyle Styer
1Fertility Center, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. jodoyle@partners.org
Objective:
To describe two cases of successful pregnancy after a rescue course of hCG in the setting of false empty follicle syndrome.
Design:
Case report.
Setting:
Academic medical center.
Patient(S):
Two patients undergoing ultrasound-guided oocyte retrieval with failure to obtain oocytes during oocyte retrieval.
Intervention(S):
Rescue course of hCG with second oocyte retrieval 35 hours later.
Main Outcome Measure(S):
Live birth.
Result(S):
Two live-birth pregnancies.
Conclusion(S):
Live-birth pregnancies are a realistic possibility after administration of a rescue course of hCG and repeat oocyte retrieval in the setting of false empty follicle syndrome.
