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Sleep-disordered breathing in premenopausal women: differences between younger (less than 30 years old) and older
Visasiri Tantrakul1, Chan-Soon Park, Christian Guilleminault
1Sleep Disorder Center Ramathibodi Hospital, Pulmonary and Critical Care Unit, Medicine Department, Mahidol University, Bangkok, Thailand. vtantrakul@gmail.com
Objective:
To compare clinical manifestations and polysomnographic data of sleep-disordered breathing (SDB) in younger (less than 30 years old) versus older premenopausal women.
Methods:
A cohort of 420 premenopausal women diagnosed with SDB in a university sleep clinic during a 5-year period underwent systematic collection of clinical and polysomnographic variables.
Results:
One-hundred and fifteen (27.4%) women were younger than 30 (mean 24.5 ± 3.5 years), while 305 (72.6%) were older than 30 (mean 39.5 ± 5.7 years). The younger premenopausal women had less severe SDB with a trend towards upper-airway resistance syndrome. Despite similar daytime consequences, snoring was less common in the younger group. Both groups of premenopausal women frequently had insomnia and nasal abnormalities or craniofacial-deficiency.
Conclusion:
Recognizing the different clinical features and understanding the different polysomnographic presentation of SDB in young premenopausal women are crucial to detecting and treating this syndrome.
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