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Factors predicting in-hospital mortality of patients with diffuse peritonitis from perforated colonic diverticulitis

Adolfo Pisanu1, Isabella Reccia, Daniela Deplano

  • 1Department of Surgery, University of Cagliari, Cagliari, Italy. adolfo.pisanu@tin.it

Annali Italiani Di Chirurgia
|May 22, 2012
PubMed
Abstract

Insights

Perforated diverticulitis is a serious condition. The Mannheim Peritonitis Index (MPI) effectively predicts mortality, with higher scores indicating increased risk, especially in older patients with delayed treatment.

Area of Science:

  • Gastroenterology
  • Surgical outcomes
  • Peritonitis

Background:

  • Perforated colonic diverticulitis presents a significant life-threatening risk.
  • Effective prognostic indicators are crucial for managing patient outcomes.

Purpose of the Study:

  • To identify factors influencing prognosis in perforated colonic diverticulitis.
  • To validate the Mannheim Peritonitis Index (MPI) for predicting mortality in these patients.

Main Methods:

  • A retrospective analysis of 39 patients operated on for generalized peritonitis due to perforated diverticulitis between 2000 and 2010.
  • A cross-sectional comparison of deceased versus non-deceased patients.

Main Results:

  • Five postoperative deaths (12.8%) occurred, primarily due to septic shock.
  • Deceased patients were significantly older, had longer symptom duration, and higher MPI scores.
  • Age, symptom duration, and MPI were independent predictors of poor prognosis.

Conclusions:

  • The Mannheim Peritonitis Index (MPI) remains a valid tool for predicting postoperative mortality in perforated diverticulitis.
  • Prompt hospitalization is vital, particularly for older individuals, to improve outcomes.

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