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A case of middle mediastinal thymoma
Yasunori Shikada1, Masakazu Katsura, Tomoyoshi Takenaka
1Department of Thoracic Surgery and Clinical Research, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jighyohama, Fukuoka, Japan. shikada0416@yahoo.co.jp
General Thoracic and Cardiovascular Surgery
|May 22, 2012
Summary
A rare middle mediastinal thymoma, diagnosed as type AB mixed thymoma, was successfully treated with surgery and radiation therapy. The patient remained disease-free for over 9 years, demonstrating effective management of this uncommon tumor.
Area of Science:
- Oncology
- Thoracic Surgery
- Pathology
Background:
- Thymoma is a rare tumor originating from the thymus gland.
- Middle mediastinal masses are uncommon, with thymoma being a rare cause.
- Early detection through routine health examinations is crucial.
Observation:
- A 56-year-old male presented with an incidental finding of a middle mediastinal abnormality on chest X-ray.
- Computed tomography confirmed a middle mediastinal tumor.
- Surgical resection was performed for diagnosis and treatment.
Findings:
- Pathological diagnosis revealed a mixed thymoma (type AB, World Health Organization Classification).
- The tumor was classified as stage II thymoma due to capsular invasion (Masaoka staging system).
- Postoperative radiation therapy (50 Gy) was administered to the mediastinum.
Implications:
- This case highlights the successful surgical and adjuvant radiation management of a rare middle mediastinal thymoma.
- Long-term disease-free survival is achievable with appropriate treatment protocols.
- Emphasizes the importance of considering thymoma in the differential diagnosis of middle mediastinal masses.

