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Updated: May 22, 2026
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An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
Published on: June 24, 2025
Catheter-related bloodstream infection caused by Enterococcus spp
E Reigadas1, M Rodríguez-Créixems, M Guembe
1Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain. helenrei@hotmail.com
Summary
Enterococcus species are an emerging cause of catheter-related bloodstream infections (CR-BSI). This study found a 17% annual increase in enterococcal CR-BSI (ECR-BSI), a serious infection with high mortality.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Enterococcus species are increasingly recognized as pathogens.
- The role of Enterococcus in catheter-related bloodstream infections (CR-BSI) is not well understood.
- Catheter-related bloodstream infections pose a significant healthcare challenge.
Purpose of the Study:
- To determine the incidence and clinical characteristics of enterococcal CR-BSI (ECR-BSI).
- To analyze trends in ECR-BSI over an eight-year period.
- To inform empirical treatment strategies for CR-BSI.
Main Methods:
- Retrospective study conducted over an 8-year period (January 2003 - December 2010).
- Involved a large teaching institution.
- Collected microbiological and clinical data from patients with ECR-BSI.
Main Results:
- ECR-BSI represented 6% of all CR-BSI and was the fourth leading cause.
- The incidence of ECR-BSI increased by 17% annually.
- Overall mortality for ECR-BSI was 33%, with 19% of episodes being polymicrobial.
Conclusions:
- Enterococcal CR-BSI is an emerging and increasingly common healthcare-associated infection.
- ECR-BSI is associated with high mortality.
- Findings necessitate consideration of Enterococcus in empirical CR-BSI treatment.
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