Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mass effect and atrophy after stroke.

E B Skriver1, T S Olsen, P McNair

  • 1Department of Neuroradiology, Hvidovre Hospital, University of Copenhagen, Denmark.

Acta Radiologica (Stockholm, Sweden : 1987)
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response to the letter to the editor: "Prevalence and predictors of neglect-like symptoms in patients with painful hand osteoarthritis".

Musculoskeletal science & practice·2023
Same author

Development of a prediction model to determine responders to conservative treatment in people with symptomatic hand osteoarthritis: A secondary analysis of a single-centre, randomised feasibility trial.

Musculoskeletal science & practice·2022
Same author

Neglect-like symptoms and their relationships with other clinical features in people with hand osteoarthritis: An exploratory study.

Musculoskeletal science & practice·2022
Same author

Six weeks of resistance training (plus advice) vs advice only in hand osteoarthritis: A single-blind, randomised, controlled feasibility trial.

Musculoskeletal science & practice·2021
Same author

Stroke case-fatality and marital status.

Acta neurologica Scandinavica·2018
Same author

Married, unmarried, divorced, and widowed and the risk of stroke.

Acta neurologica Scandinavica·2018

Ischemic stroke can cause cerebral edema and atrophy. Large infarcts frequently lead to significant mass effect and subsequent cerebral atrophy, impacting stroke recovery.

Area of Science:

  • Neurology
  • Radiology
  • Pathology

Background:

  • Ischemic stroke is a leading cause of disability.
  • Cerebral edema and atrophy are common complications following stroke.
  • Understanding the temporal evolution of these changes is crucial for patient management.

Purpose of the Study:

  • To prospectively evaluate the development and resolution of cerebral edema and atrophy after ischemic stroke.
  • To correlate infarct size with the extent of mass effect and subsequent atrophy.
  • To assess changes in specific CT-measured parameters indicative of edema and atrophy.

Main Methods:

  • Prospective study of 83 ischemic stroke patients.
  • Serial CT scans at 3 days, 2 weeks, and 6 months post-stroke.

Related Experiment Videos

  • Measurement of Evans' ratio (ER), septum-caudate distance (S/C), and widest cortical sulci (SuW) as markers of mass effect/atrophy.

    • Main Results:

    • Mass effect observed in 81% and atrophy in 58% of patients with large infarcts (diameter > 3 cm).
    • Mass effect occurred in 38% and atrophy in 45% of patients with medium-sized infarcts (1.5-3 cm).
    • Individual CT parameter changes became apparent when comparing serial scans, indicating evolving mass effect and atrophy.

    Conclusions:

    • Infarct size is a significant predictor of mass effect and subsequent cerebral atrophy.
    • Serial CT imaging is essential to detect evolving mass effect and atrophy post-stroke.
    • These findings highlight the importance of monitoring for edema and atrophy in stroke patients, particularly those with larger infarcts.